Breast Cancer
Publié le 09/11/2015
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A new advancement in breast cancer radiation therapy called intraoperative
radiation therapy, or IORT, is a promising treatment that may help alleviate
some of this burden for women with earlystage disease.
Used successfully for decades with a different type of radiation therapy as
part of treatment for intraabdominal cancers, a new type of IORT is now
being used to deliver high doses of radiation during lumpectomies,
concentrated only in the cavity where tumors were removed.
After excising the tumor and surrounding tissue from the breast, radiation is
delivered through an applicator directly to the former tumor’s site, where the
risk of cancer recurrence is highest.
Shielding of the rest of the body is not required as the radiation is focused
only in the lumpectomy cavity and the focused radiation does not damage the
heart or lungs—as can happen with whole breast radiation. After about 30
minutes of treatment, the applicator is removed.
The single dose of intraoperative radiation delivers a single very high dose of
radiation to the area around the lumpectomy cavity—different from traditional
whole breast radiation, which delivers multiple small doses over many days.
Based on the results of a large clinical trial, focusing the radiation on the
tumor bed, IORT has been shown to be as effective as whole breast radiation
for selected patients with early stage breast cancer: the rate of cancer
recurrence is comparable after both forms. The study also showed the risk of
skin toxicity is decreased after IORT compared to conventional radiation
therapy.
Intraoperative radiation therapy is significantly less costly than standard
whole breast radiation treatment. And with fewer trips made to the hospital for
radiation therapy planning and radiation therapy and less time spent in
treatment, intraoperative radiation therapy provides a significant boost to the
quality of life for patients with early stage breast cancer.
https://www.youtube.com/watch?v=Z91GUWiRGdU. »
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